potassiumchannels相关论文
先证者为8岁男性患儿，双眼视力进行性下降3年，视网膜电图表现为独特的闪光视网膜电图波形，视杆和视锥系统反应下降；但暗适应状态高刺激......
Protein turnover and homeostasis is regulated by proteasomal system,which is essential in keeping cell viability and nor......
Galanin suppresses neuronal excitability in the rat locus coeruleus via activation of G-protein-coup
The central prominent noradrenergic locus coeruleus(LC)neurons are involved in a variety of brain functions including sl......
AIM The purpose of this study was to study the influence of KCNE4 on potassium ion channel KCNQ 1 and HERG.Method We con......
Bone marrow mesenchymal stem cells reversed potassium channels remodeling in post-infarcted myocardi
Aim: Bone marrow mesenchymal stem cells (BMSCs) emerge as a new promising approach for treating heart diseases.However, ......
SUMO-specific protease 2 is critical for the regulation of M-current through PLCb4 and Kv7 pathway d
Sudden unexplained death in epilepsy(SUDEP)is the most common and primary cause of premature mortality in epilepsy.Hyper......
Activation of ATP-sensitive potassium channels antagonize nociceptive behavior and hyperexcitability
Nociceptive responses to noxious stimuli are initiated at peripheral nociceptor terminals.Ion channels play a vital role......
Purpose: Recently,it has been shown that the medial parabrachial nucleus(MPB)is a novel wake-promoting component in the ......
Central neurons encode information in bursts of action potentials (APs/spikes), but little is known about the gating beh......
Genetic variants of rs1275988 and rs2586886 in TWIK-related acidsensitive K+ channel-1 gene may be p
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Objective To deter mice the role of glucose in the control of insulin secretion and the possible mechanisms with which ......
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Potassium channels are a broad family of membrane proteins present in almost every cell,and their rapid and highly s......
Sudden unexplained death in epilepsy(SUDEP),which is the most common and primary cause of premature mortality in epi......
Ion channels selective for potassium (K+ channels) are involved in fine-tuning a plethora of physiological functions, su......
妊娠期高血压疾病（ HDCP）是孕产妇和围生儿病死率升高的主要原因，目前对其发病机制的研究已经进入到基因、分子水平。离子通道的改变......
癫痫是儿童神经系统最常见的疾病之一，遗传因素是其重要病因。而遗传性钾离子通道改变与癫痫发生的关系是近年来的研究热点与难点。......
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目的 探讨ATP敏感性钾通道(KATP)激动剂Cromakaliam(CRK)对离体豚鼠心室肌细胞瞬间内向电流(Transient Inward Current,Iti)的作用......
目的 探讨电压门控钾离子通道(Kv)对人绒毛膜促件腺激素(hCG)诱导的卵巢黄素化颗粒细胞增殖、分泌及凋亡的影响.方法 收集2007年11......
目的 评价线粒体ATP敏感性钾通道在头部浅低温减轻大鼠全脑缺血再灌注损伤中的作用.方法 健康雄性SD大鼠32只,体重200～250 g,随机分......
目的：观察膜环境高温对下丘脑神经瞎迟整流性Ｋ＾＋通道（Ｉｇ）电压依赖性的影响。方法：采用细胞贴附式的片钳技术。结果：高温可影响通道的电压依赖......
目的评价一种药理学中分析电压依赖性瞬时外向钾电流(Ito)的积分方法.方法 Ito的失活相可被2指数或3指数方程拟合.原始电流曲线下......
